Coronavirus is a contagious virus that has never spread to humans before in the world. The death toll from the virus worldwide is about 1.5 million. The number of identities worldwide is more than 6 crore. (Data updated 4th January 2021)
The whole world is under the influence of coronavirus. The full name of this deadly Chinese virus - Novel Corona Virus or 2019-NCOV. This new version of the coronavirus was first detected in the human body in Wuhan, Hubei Province, China. Since then, the corona has spread to about 14 provinces in China. Even in Thailand, Singapore, South Korea, Taiwan, Malaysia, several people have died from the coronavirus. In China alone, about 600 people have already died.
The primary symptoms of coronary heart disease are sore throat, fever, headache, severe shortness of breath, etc. Much like pneumonia. In fact, the coronavirus lurks behind the familiar symptoms. Its bite is horrible. The infection is not immediately understood. It takes 2 to 14 days for the symptoms to manifest. The way to deal with this virus is still elusive in science.
What is a virus: A virus is a type of microscopic object or particle. And not like the five germs. They are acellular. Behaves like an inanimate object in an independent state. Viruses are binding parasites due to their non-cellular nature, which are responsible for a number of important and contagious diseases in the body of various animals, including specific bacteria, plants, and humans. They are incapable of independent reproduction. But when they enter the cell, they become alive and capable of self-reproduction. In the end, it destroys the host cell by holding the image of destruction.
Characteristic of corona: Each virus is surrounded by a tight shell of protein. This is called a capsid. The packaging of the capsid contains nucleic acids - DNA or RNA. In the case of coronaviruses, the capsid contains a monolayer, a positive RNA, which coils like a coil. The word coronavirus comes from the Latin word. The name Corona means ‘crown’ or ‘luminosity of the sun’. Because that's what they look like under an electron microscope. The coronavirus, a new species from China, has been named '2019 NCOV'. This means that the existence of this virus has been known in 2019. ‘N’ or novel which means new or fancy, ‘CO’ does not mean corona and ‘V’ means a virus.
Like other animal viruses, coronaviruses contain an envelope of extra protein-lipids in the capsid. On the outside of this mantle are protruding projections like thorns or alpin. It's called a spike. Large spikes are made up of glycoprotein compounds. Small spikes are made up of hemoglobin protein. This protein acts as an antigen and turns red blood cells into lumps after entering the human body.
How to invade: Among the animal viruses, the coronavirus and many of its relatives combine to form a large corona viridi family. Each of them uses the body of one or the other animal as a host to carry out the task of reproduction for their own needs. The virus only attacks specific host cells. This trait is controlled by genes in the virus's DNA or RNA.
The question here is, how does the coronavirus enter a new animal or human body from a specific animal? Behind this is the mutation of the virus. Viruses are sensitive to different conditions of the environment and this is why they can adapt to the changing conditions of the environment. This religion of the virus is called a mutation. Scientists believe that this mutation helped the coronavirus to adapt to humans. Gene's manipulation is also involved in this incident.
Genetic mutations: The genetic mutations of coronaviruses are essential for their mutation and death. The purpose is the same. Whether new or old, the virus forcibly seizes or snatches the host cell infrastructure. They take care of the breeding work for their own needs. Genetic mutations cause various structural changes in the virus. According to scientists, this change also changes the projection of the virus.
Genes control all traits. Multiple genes have a specific sequence. Subtle changes in the basic alkaline component of this sequence or gene result in genetic changes and changes in the character of the organism. Why the risk of genetic changes in the case of corona? The issue of genetic modification of corona has come from the source of mutation. Genetic changes occur, especially in the case of animal viruses. The genome mystery of this mutating and mutating virus is making scientists dizzy.
In the case of animal viruses, when the virus attacks the host cell, the virus binds to the receptor located in the host cell by projection. If the structure of the virus projection does not change during the change of host, the new host will not stick to the receptor of the cell. As a result, attempts to enter new host cells will fail. But if successful, the attack will intensify. This success is making the virus increasingly unrecognizable. The corona attaches to a receptor called angiotensin-converting enzyme 2, or ACE-2, located in the cell membrane through its altered glycoprotein spike. Once injected into the host cell, the virus injects itself into the RNA cell during injection, or the entire virus enters the endocytosis process. Later the capsid portion is removed. Then nomologically positive RNA is made into monologue negative RNA. Using that as a mold, using the synergistic technique of the host cell, a number of positive units, such as photocopies, are created.
